How CBD Helps in Case of Alzheimer’s DiseaseAlzheimers and cbd

Although the usual and conventional treatments for Alzheimer’s disease can alleviate or ease up the symptoms, the drugs can’t delay or reverse the progression of the disease. Recent studies, however, showed CBD has positive effects on Alzheimer’s disease. CBD was also found to have a role in the treatment of Alzheimer’s disease.

Alzheimer’s disease

Alzheimer’s disease is actually a neurodegenerative and chronic disorder that is usually linked to the progressive cognitive decline and neuronal loss, which normally affects elderly or aged patients between the age of sixty-five and eighty years. The cause is actually multi-factorial that includes unknown etiology and to some extent, genetic basis. Patients suffering from Alzheimer’s disease usually suffer from cognitive impairment, long and short-term memory loss & difficulty in speaking. Alzheimer’s disease is actually characterized by aggressive behavior, psychosis, and depression. The patients usually become more dependent on caregivers and family as the disease progresses to later stages. Although the usual or conventional treatments of the Alzheimer’s disease, like acetylcholine-esterase inhibitors can help in alleviating the symptoms, acetylcholine-esterase inhibitors cannot reverse or delay the disease progression.

Alzheimer ’s disease and CBD

A very disturbing and dramatic symptom of the Alzheimer’s disease is the patient’s inability to recognize people or places; there are patients who cannot even recognize their children and close relatives. Past research and studies proved that CBD has beneficial effects in the treatment of the Alzheimer’s disease because of CBD’s neuroprotective, antioxidant, and anti-inflammatory effects. Studies have also determined that CBD (cannabidiol) can effectively reduce the further buildup of tangles and plagues, and further showed viable and reliable potential benefits that can be very useful in the treatment of AD (Alzheimer’s disease).

The potential efficacy of CBD for the Alzheimer’s disease can be associated with its interaction with endocannabinoid system that modulates many pathological processes related to the neurodegenerative disorder such as mitochondrial dysfunction, excitotoxicity, oxidative stress, and neuroinflammation. The brain of the patients suffering from Alzheimer’s disease experience the microglia’s over activation. Microglia is actually cells, which form myelin. This over-activation of microglia further contributes to the excessive build-up of tau & eventually tangles.

The CBD, however, has been proved to modulate the microglial function & control the neuroinflammation. In addition to that, the CBD has also been proved to help in improving the cells’ survival rate through the combination of anti-apoptotic, anti-inflammatory, anti-oxidative, and neuroprotective effects against harmful effects or toxicity that is caused by the beta-amyloid and, therefore, showing great potential as one effective therapeutic option or treatment for the Alzheimer’s disease.

Cannabinoids or CBD provide one multi-faceted approach towards the treatment and management of the Alzheimer’s disease. CBD contributes to the reduction in the levels of amyloid-beta, increasing the glucose uptake, and modulating the microglial function. CBD also offers protection to the cells in the brain from the amyloid-beta’s harmful effects, reduce inflammation & supports the repair process of the brain by enhancing the neurogenesis & offering neuroprotective effects.

Conclusion

It was proved in many studies that the plant-derived terpenoids like cannabinoids (CBD) possess outstanding therapeutic potential and benefits proved in the treatment of Alzheimer’s disease. They have also shown to help in improving aggression, communication, and agitation in those who are diagnosed with Alzheimer’s disease.

 

Cannabis and Alzheimer’s Disease – Short Documentary

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